PAR-2 is the second member of the family of proteinase-activated receptors activated by trypsin, tryptase, and several other serine proteinases.In order to evaluate the therapeutic potential for PAR-2, we have performed studies on PAR-2-mediated signal transduction and investigated the effects chervo jacke herren of PAR-2 gene deficiency in disease
Positive end-expiratory pressure and prone position alter the capacity of force generation from diaphragm in acute respiratory distress syndrome: an animal experiment
Abstract Background Spontaneous breathing potentially injures lungs and diaphragm when spontaneous effort is vigorous in acute respiratory distress syndrome (ARDS) while immobility also has risks of Intensive Care Unit (ICU) acquired weakness and rivolis las vegas diaphragm atrophy.Thus, ventilatory strategy to mitigate strong spontaneous effort sh
Effectiveness of an Education Program to Reduce Negative Attitudes Toward Persons With Mental Illness Using Online Media
The purpose of this study was to develop an educational program to reduce negative attitudes toward persons with mental illness (PMIs) using online media and to test its effectiveness.Methods: A nonequivalent control group with a pre-posttest was employed in this study.A total of whirlwind direct2 143 lay people were enrolled.The study variables we
CavitySpace: A Database of Potential Ligand Binding Sites in the Human Proteome
Location and properties of ligand binding sites provide important information to uncover protein functions and to direct structure-based drug design approaches.However, as binding site detection depends on the three-dimensional (3D) structural data of proteins, functional analysis based on protein ligand binding sites is formidable for proteins wit